VecNet Digital Library

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A geographic information system applied to a malaria field study in western Kenya

Hightower, AW, Ombok, M, Otieno, R, Odhiambo, R, Oloo, AJ, Lal, AA, Nahlen, BL, Hawley, WA
The American Journal of Tropical Medicine and Hygiene 58(3), 266-72. (1998-03)

This paper describes use of the global positioning system (GPS) in differential mode (DGPS) to obtain highly accurate longitudes, latitudes, and altitudes of 1,169 houses, 15 schools, 40 churches, four health care centers, 48 major mosquito breeding sites, 10 borehole wells, seven shopping areas, major roads, streams, the shore of Lake Victoria, an...

Antibody responses to repetitive epitopes of the circumsporozoite protein, liver stage antigen-1, and merozoite surface protein-2 in infants residing in a Plasmodium falciparum-hyperendemic area of western Kenya. XIII. Asembo Bay Cohort Project

Zhou, Z, Xiao, L, Branch, OH, Kariuki, S, Nahlen, BL, Lal, AA
The American Journal of Tropical Medicine and Hygiene 66(1), 7-12. (2002-01-1)

The present study was initiated to characterize antibody responses to repetitive epitopes of the circumsporozoite protein (CSP), liver stage antigen-1 (LSA-1), and merozoite surface protein-2 (MSP-2) of Plasmodium falciparum in infants residing in a P. falciparum-hyperendemic area of western Kenya. In this study, development and maintenance of thes...

Community-wide effects of permethrin-treated bed nets on child mortality and malaria morbidity in Western Kenya

Hawley, WA, Phillips-Howard, PA, Ter Kuile, FO, Terlouw, DJ, Vulule, JM, Ombok, M, Nahlen, BL, Gimnig, JE, Kariuki, SK, Kolczak, MS
American Journal of Tropical Medicine and Hygiene 68(90040). (2003)

Effects of permethrin-treated bed nets on immunity to malaria in western Kenya I. Antibody responses in pregnant women and cord blood in an area of intense malaria transmission

Kariuki, SimonK, Ter Kuile, FeikoO, Wannemuehler, Kathleen, Terlouw, DianneJ, Kolczak, MargaretteS, Hawley, WilliamA, Phillips-Howard, PenelopeA, Orago, AlloysSS, Nahlen, BernardL, Lal, AltafA, Shi, YaPing
The American Journal of Tropical Medicine and Hygiene 68(4suppl), 61-67. (2003-04-1)

As part of a community-based group-randomized trial on the impact of permethrin-treated bed nets (ITNs) on malaria in pregnancy in a holoendemic area of western Kenya, we assessed their effects on antibody responses to Plasmodium falciparum pre-erythrocytic antigens (recombinant circumsporozoite protein [CSP] and peptides complimentary to the repea...

Effects of permethrin-treated bed nets on immunity to malaria in western Kenya II. Antibody responses in young children in an area of intense malaria transmission

Kariuki, SimonK, Lal, AltafA, Terlouw, DianneJ, Ter Kuile, FeikoO, Ong’echa, JohnMO, Phillips-Howard, PenelopeA, Orago, AlloysSS, Kolczak, MargaretteS, Hawley, WilliamA, Nahlen, BernardL, Shi, YaPing
The American Journal of Tropical Medicine and Hygiene 68(4suppl), 108-114. (2003-04-1)

As part of a large community-based trial on the impact of insecticide (permethrin)-treated bed nets (ITNs) on childhood morbidity and mortality in an area of intense perennial malaria transmission in western Kenya, we assessed the effects of ITNs on malaria-specific humoral responses in young children. The IgG responses to Plasmodium falciparum pre...

Evaluation of fenitrothion for the control of malaria

Fontaine, RE, Pull, JH, Payne, D, Pradhan, GD, Joshi, GP, Pearson, JA, Thymakis, MK, Camacho, ME
Bulletin of the World Health Organization 56(3), 445-52. (1978)

Fenitrothion was evaluated for residual spraying in antimalaria programmes in a large-scale field trial near Kisumu, Kenya from 1972 to 1976. The insecticide was applied in a hyper/holoendemic malarious area of 200 km(2) inhabited by about 50 000 people. All houses and animal shelters were sprayed at a target dosage rate of 2 g/m(2) at 3-month inte...

Evaluation of fenitrothion (OMS 43) for malaria control in a large-scale epidemiological trial, Kisumu, Kenya

Fontaine, RE, Pull, J, Payne, D, Pradhan, GD, Joshi, G, Pearson, JA

Fenitronthion, an organophosphorus insecticide, was evaluated for residual spraying in antimalaria programmes in a large-scale field trial near Kisumu, Kenya from August 1972 to June 1976. The project involved entomological, parasitological and toxicological evaluation of the insecticide applied in a hyper/holo-endemic malarious area covering 200 k...

Exposure to holoendemic malaria results in elevated epstein-barr virus loads in children

Moormann, AnnM, Chelimo, Kiprotich, Sumba, OdadaP, Lutzke, MaryL, Ploutz-Snyder, Robert, Newton, Duane, Kazura, James, Rochford, Rosemary
Journal of Infectious Diseases 191(8), 1233-1238. (2005-04-15)

Perennial and intense malaria transmission (holoendemic malaria) and Epstein-Barr virus (EBV) infection are 2 cofactors in the pathogenesis of endemic Burkitt lymphoma (eBL). In the present study, we compared EBV loads in children living in 2 regions of Kenya with differing malaria transmission intensities: Kisumu District, where malaria transmissi...

Field trial of permethrin impregnated sisal curtains in malaria control in western Kenya

Oloo, A., Githeko, A., Adungo, D., Karanja, J., Vulule, J., Kisia-Abok, I., Seroney, I., Ayisi, J., Ondijo, S., Koech, D. K., Abdullah, M. S.
East Afr Med J 73(11), 735-740. (1996)

A trial to determine the effectiveness of sisal eaves-curtains impregnated with permethrin for malaria control was conducted in the malaria holoendemic western Kenya between 1991 and 1993. Indoor resting densities of Anopheles gambiae s.l. and Anopheles funestus were reduced. by 90.9% and 93.8% respectively in protected houses, The entomological in...

Impact of control measures on malaria transmission and general mortality

Payne, D, Grab, B, Fontaine, RE, Hempel, JHG
Bulletin of the World Health Organization 54(4), 369-377. (1976)

This paper is an attempt to relate modifications observed in general and infant mortality rates with the dynamic changes in transmission induced by malaria control measures. The observations indicated relationships between the efficacy of control and a decrease in mortality. The daily parasitological inoculation rate was reduced from 0.00958 infect...